IN VIVO ANALYSIS OF CRISPR-EDITED GERMINAL CENTER MURINE B CELLS

In vivo analysis of CRISPR-edited germinal center murine B cells

The germinal center (GC) reaction is crucial for somatic hypermutation, affinity maturation, and the selection of high-affinity B cells, all of which are hallmarks of the humoral immune response.Understanding the distinct roles of various B cell genes is essential for elucidating the selection mechanisms within the GC reaction.Traditionally, studyi

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The Impact of Openness on Bridging Educational Digital Divides

Openness has been a feature of higher education for many decades, particularly through the establishment of open universities, although there remain debates about what openness means in practice.Digital technologies, some based on open principles, and digital content, aided by open licences, have both contributed recently to an extension of what is

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